![]() ![]() This NEJM-based study may be limited in generalizability. 6Įvaluation by multivariable regression analyses reconfirmed that an author publishing clinical trials (odds ratio = 6.9, 95% CI P = 0.0011) with grant-funding (OR = 1.7, 95% CI P = 0.0085) was more likely to be an MP author holding CVD-related topic, coauthor count, and collaborating author count constant. Although not definitive, these pilot findings suggest there may be a publication bias for first-time studies reporting positive findings submitted to and/or published in NEJM furthermore, these pilot study results appear consistent with prior findings on publication bias. For the subgroup of MP authors, this tendency to report neutral or negative findings more often was not unique to clinical trial-based ( P = 0.326) or CVD-related publications ( P = 0.129). There was a strong trend against neutral or negative findings being reported, though MP first authors did so more often than SP first authors (27% vs. Overall, female first authors appeared to be underrepresented for both SP and MP first authors (13% n = 36/273).Ībstracts were reviewed to summarize each publication’s findings as positive, negative, or no differences found. 67% P = 0.968) or difference in Massachusetts-based institutional affiliation (12% vs. 8% P = 0.746], difference in North American location (67% vs. 8% P = 0.554), clinical specialty difference (i.e., medical specialty = 72% vs. For this pilot study evaluating MP and SP first author differences, there was no statistically significant female gender difference (14% vs. ![]() combined doctoral degrees) were evaluated. MP first author characteristics of gender, institutional location (i.e., North America-based or Massachusetts-based, the state in which NEJM is based), self-designated major clinical specialty, and advanced degrees held (i.e., clinical vs. Using this supplementary data, the SP vs. 80% P 80% agreement and Kappa upwards of 0.7, thus indicating good concordance between these two raters. ![]() Compared to SP first authors, MP first authors more often published clinical trials (96% vs. Results: There were 2,065 first authors identified, of which 88% (n = 1,816) were SP first authors these 1,816 SP first authors represented 75% of publications. First author-specific characteristics included gender, advanced degrees held, self-designated major clinical specialty, institutional location, and academic rank. Main Outcome(s) and Measure(s): Publication-specific characteristics included National Library of Medicine medical subject headings disease category, clinical trial design, grant funding, coauthor count, collaborating author count, and other study-specific details (e.g., directionality of overall findings). Participants/Exposure: The NEJM author and research project characteristics were compared for the first authors with multiple first author publications (MP) vs. For a sampling of articles, supplementary information was obtained from publicly available resources. Objectives: To support scientific transparency, the “unwritten” NEJM publication priorities and trends were documented.ĭesign/Setting: From 2002 to 2017, PubMed extracts for all original NEJM research articles with a structured abstract (n = 2,419) were analyzed. Importance: High-impact journals (e.g., New England Journal of Medicine ) transform clinical practice these publications have been commonly used to quantify faculty performance in academic medical centers’ promotion and tenure decisions. ![]()
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